Across TCGA cell cohorts, SPANXA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 562 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SPANXA1-associated GO terms across cancer lineages are Chaperone-mediated autophagy, Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, and Positive regulation of ATP biosynthetic process. Each is linked with SPANXA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPANXA1-to-partner and partner-to-SPANXA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXA1→partner) and Y-score (partner→SPANXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Chaperone-mediated autophagy →	+0.111	+1.048	<.001	.009	3	6
LIVER	Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.116	+4.909	<.001	<.001	3	5
LIVER	Positive regulation of ATP biosynthetic process →	+0.200	+4.240	.001	<.001	3	5
LIVER	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.207	+3.215	.002	<.001	3	5
LIVER	Keratinocyte development →	+0.404	+4.203	.001	<.001	3	5
BLOOD_Lymphoma	Vesicle cargo loading →	+0.050	+0.114	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 562 associations by consensus.

Exploration

SPANXA1 survival (RNA) · tumor vs normal (RNA) · all SPANXA1 data types