SPAG7

Across TCGA cell cohorts, SPAG7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,498 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPAG7-associated GO terms across cancer lineages are Eosinophil activation involved in immune response, Eosinophil activation, and Eosinophil degranulation. Each is linked with SPAG7 in more than 10 cancer types. Because this analysis shows association rather than direction, both SPAG7-to-partner and partner-to-SPAG7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophil activation involved in immune response grouped by SPAG7-low versus SPAG7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG7→partner) and Y-score (partner→SPAG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Eosinophil activation involved in immune response →	+0.170	+0.895	<.001	<.001	3	11
BREAST	Eosinophil activation →	+0.170	+0.895	<.001	<.001	3	11
BREAST	Eosinophil degranulation →	+0.170	+0.895	<.001	<.001	3	11
LUNG_NSCLC_LUSC	D-amino acid metabolic process →	+1.562	+1.175	.001	<.001	3	10
OVARY	Corpus callosum morphogenesis →	+0.075	+0.628	<.001	<.001	3	10
URINARY_TRACT	Postsynaptic density protein 95 clustering →	+1.175	+0.672	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,498 associations by consensus.

Eosinophil activation involved in immune response by SPAG7 expression — BREAST

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