Across TCGA patient cohorts, SPAG5-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,134 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPAG5-AS1-associated proteins across cancer lineages are DHX9, PARP1, and SF3B3. Each is linked with SPAG5-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPAG5-AS1-to-partner and partner-to-SPAG5-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG5-AS1→partner) and Y-score (partner→SPAG5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.224	+0.372	<.001	<.001	3	6
HNSC	PARP1 →	+0.485	+0.536	<.001	<.001	3	5
LSCC	SF3B3 →	+0.208	+0.379	<.001	<.001	3	5
LSCC	EIF4A3 →	+0.189	+0.381	<.001	<.001	3	5
LSCC	SUPT6H →	+0.295	+0.450	<.001	<.001	3	5
UCEC	PDLIM1 →	-0.372	-0.387	.004	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,134 associations by consensus.

Exploration

SPAG5-AS1 survival (RNA) · tumor vs normal (RNA) · all SPAG5-AS1 data types