Across TCGA patient cohorts, SPAG16-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,117 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPAG16-DT-associated GO terms across cancer lineages are Intraciliary anterograde transport, Microtubule-based transport, and Protein localization to ciliary membrane. Each is linked with SPAG16-DT in more than 26 cancer types. Because this analysis shows association rather than direction, both SPAG16-DT-to-partner and partner-to-SPAG16-DT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG16-DT→partner) and Y-score (partner→SPAG16-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Intraciliary anterograde transport →	+0.053	+0.114	<.001	<.001	3	27
ESCA	Microtubule-based transport →	+0.038	+0.131	<.001	<.001	3	26
UVM	Protein localization to ciliary membrane →	+0.056	+0.199	<.001	.002	2	27
STAD	Positive regulation of double-strand break repair →	+0.054	+0.080	<.001	<.001	3	26
ESCA	Positive regulation of double-strand break repair via homologous recombination →	+0.058	+0.124	<.001	<.001	3	25
ESCA	Non-motile cilium assembly →	+0.048	+0.121	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,117 associations by consensus.

Exploration

SPAG16-DT survival (RNA) · tumor vs normal (RNA) · all SPAG16-DT data types