SPAG11B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPAG11B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,479 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPAG11B-associated GO terms across cancer lineages are Neural tube formation, Dorsal/ventral neural tube patterning, and Primary miRNA processing. Each is linked with SPAG11B in more than 5 cancer types. Because this analysis shows association rather than direction, both SPAG11B-to-partner and partner-to-SPAG11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neural tube formation grouped by SPAG11B-low versus SPAG11B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG11B→partner) and Y-score (partner→SPAG11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNeural tube formation →+0.079+0.065<.001<.00136
STADDorsal/ventral neural tube patterning →+0.055+0.053<.001<.00136
STADPrimary miRNA processing →+0.078+0.063<.001<.00136
STADEnteroendocrine cell differentiation →+0.058+0.073<.001<.00136
STADPositive regulation of plasma membrane bounded cell projection assembly →+0.078+0.064<.001<.00136
STADAppendage development →+0.061+0.067<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,479 associations by consensus.

Neural tube formation by SPAG11B expression — STAD

Box plot of Neural tube formation in SPAG11B-low vs SPAG11B-high samples in STAD.

Explore this box plot interactively →

Exploration