SPAG11B

Across TCGA cell cohorts, SPAG11B RNA expression is significantly associated with the mutation status of many other genes, with 33 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SPAG11B-associated genes across cancer lineages are FGD6, CACNA1F, and FBL. Each is linked with SPAG11B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPAG11B-to-partner and partner-to-SPAG11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGD6 grouped by SPAG11B-low versus SPAG11B-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG11B→partner) and Y-score (partner→SPAG11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FGD6 →	+3.256	+0.951	.005	.005	3	2
PANCREAS	CACNA1F →	+5.614	+0.143	.002	<.001	3	1
PANCREAS	FBL →	+5.614	+0.143	.002	<.001	3	1
PANCREAS	PEPD →	+4.614	+0.107	.004	<.001	3	1
PANCREAS	NBPF20 →	+4.614	+0.107	.004	<.001	3	1
PANCREAS	ADAMTS9 →	+5.614	+0.143	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

FGD6 by SPAG11B expression — LUNG_SCLC

Explore this box plot interactively →