SPAG11B

Across TCGA cell cohorts, SPAG11B mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SPAG11B-associated genes across cancer lineages are PRG3. Each is linked with SPAG11B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPAG11B-to-partner and partner-to-SPAG11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRG3 grouped by SPAG11B-low versus SPAG11B-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG11B→partner) and Y-score (partner→SPAG11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRG3 →	+0.033	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PRG3 by SPAG11B expression — LUNG_SCLC

Explore this box plot interactively →