SPACA9

Across TCGA patient cohorts, SPACA9 protein abundance is significantly associated with the RNA expression of many other genes, with 1,880 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPACA9-associated genes across cancer lineages are SPEF1, RP1, and CCDC114. Each is linked with SPACA9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPACA9-to-partner and partner-to-SPACA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPACA9 versus SPEF1 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA9→partner) and Y-score (partner→SPACA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+2.120	+1.035	.007	<.001	3	3
UCEC	RP1 →	+1.453	+0.906	.005	<.001	3	3
UCEC	CCDC114 →	+1.217	+0.635	.001	<.001	3	3
UCEC	RSPH4A →	+1.813	+0.819	.005	<.001	3	3
UCEC	PACRG →	+1.316	+0.787	.006	.002	3	3
UCEC	C6orf118 →	+1.860	+0.856	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,880 associations by consensus.

SPACA9 vs SPEF1 — UCEC

Explore this scatter interactively →