SPACA5B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPACA5B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,394 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPACA5B-associated GO terms across cancer lineages are Autophagy of mitochondrion, Vacuolar transport, and Methylation. Each is linked with SPACA5B in more than 15 cancer types. Because this analysis shows association rather than direction, both SPACA5B-to-partner and partner-to-SPACA5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by SPACA5B-low versus SPACA5B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA5B→partner) and Y-score (partner→SPACA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADAutophagy of mitochondrion →+0.065+0.061<.001<.001316
STADVacuolar transport →+0.066+0.058<.001<.001316
STADMethylation →+0.049+0.062<.001<.001315
STADEstablishment of protein localization to membrane →+0.053+0.046<.001<.001314
STADGlycerophospholipid biosynthetic process →+0.055+0.059<.001<.001314
STADProtein polyubiquitination →+0.062+0.064<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,394 associations by consensus.

Autophagy of mitochondrion by SPACA5B expression — STAD

Box plot of Autophagy of mitochondrion in SPACA5B-low vs SPACA5B-high samples in STAD.

Explore this box plot interactively →

Exploration