SPACA5B

Across TCGA cell cohorts, SPACA5B RNA expression is significantly associated with the mutation status of many other genes, with 52 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SPACA5B-associated genes across cancer lineages are B4GALNT4, EXPH5, and TIMELESS. Each is linked with SPACA5B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPACA5B-to-partner and partner-to-SPACA5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B4GALNT4 grouped by SPACA5B-low versus SPACA5B-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA5B→partner) and Y-score (partner→SPACA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	B4GALNT4 →	+5.662	+0.042	.002	<.001	3	2
SOFT_TISSUE	EXPH5 →	+4.369	+0.681	.008	<.001	3	1
SOFT_TISSUE	TIMELESS →	+5.369	+0.657	.004	<.001	3	1
SOFT_TISSUE	OGFRL1 →	+5.369	+0.909	.004	<.001	3	1
SOFT_TISSUE	TTLL4 →	+4.369	+0.681	.008	<.001	3	1
SOFT_TISSUE	LATS2 →	+5.369	+0.909	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

B4GALNT4 by SPACA5B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →