SPACA4

Across TCGA patient cohorts, SPACA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,567 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPACA4-associated proteins across cancer lineages are FAM83E, FAM83E_S351, and CEACAM5. Each is linked with SPACA4 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPACA4-to-partner and partner-to-SPACA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPACA4 versus FAM83E in BRCA, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA4→partner) and Y-score (partner→SPACA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM83E →	+1.016	+1.396	<.001	<.001	3	7
BRCA	FAM83E_S351 →	+1.773	+1.452	<.001	<.001	3	7
UCEC	CEACAM5 →	+1.278	+0.869	.001	.001	3	6
BRCA	STARD10 →	+0.772	+0.961	<.001	<.001	3	5
PDAC	CORO2A →	+0.460	+0.639	<.001	.001	3	5
LUAD	FAM83E_S324 →	+0.418	+0.888	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,567 associations by consensus.

SPACA4 vs FAM83E — BRCA

Explore this scatter interactively →