SP7

Across TCGA patient cohorts, SP7 RNA expression is significantly associated with the RNA expression of many other genes, with 8,906 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SP7-associated genes across cancer lineages are BACH2, ADAMTS10, and NAP1L3. Each is linked with SP7 in more than 14 cancer types. Because this analysis shows association rather than direction, both SP7-to-partner and partner-to-SP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SP7 versus BACH2 in THYM, with a Pearson correlation of 0.34.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP7→partner) and Y-score (partner→SP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	BACH2 →	+0.945	+0.059	<.001	<.001	3	14
LAML	ADAMTS10 →	+1.062	+0.414	.001	.003	2	15
SCLC	NAP1L3 →	+1.571	+0.073	<.001	<.001	3	13
MESO	TCF4 →	+1.182	+0.276	<.001	.001	3	13
SARC	NUDT10 →	+1.154	+0.527	<.001	<.001	2	14
LGG	SHANK1 →	+0.731	+0.121	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,906 associations by consensus.

SP7 vs BACH2 — THYM

Explore this scatter interactively →