SP7

Across TCGA patient cohorts, SP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,901 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SP7-associated GO terms across cancer lineages are Mesenchyme morphogenesis, Mesenchymal cell differentiation, and Bone morphogenesis. Each is linked with SP7 in more than 16 cancer types. Because this analysis shows association rather than direction, both SP7-to-partner and partner-to-SP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesenchyme morphogenesis grouped by SP7-low versus SP7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SP7→partner) and Y-score (partner→SP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mesenchyme morphogenesis →	+0.054	+0.138	<.001	<.001	3	17
STAD	Mesenchymal cell differentiation →	+0.052	+0.136	<.001	<.001	3	16
STAD	Bone morphogenesis →	+0.082	+0.206	<.001	<.001	3	16
STAD	Cardiac septum morphogenesis →	+0.083	+0.183	<.001	<.001	3	16
STAD	Heart morphogenesis →	+0.048	+0.126	<.001	<.001	3	16
ESCA	Epigenetic regulation of gene expression →	+0.062	+0.111	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,901 associations by consensus.

Mesenchyme morphogenesis by SP7 expression — STAD

Explore this box plot interactively →