SP7

Across TCGA cell cohorts, SP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 892 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SP7-associated GO terms across cancer lineages are Renal vesicle formation, Metanephric renal vesicle formation, and Epigenetic regulation of gene expression. Each is linked with SP7 in more than 7 cancer types. Because this analysis shows association rather than direction, both SP7-to-partner and partner-to-SP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal vesicle formation grouped by SP7-low versus SP7-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SP7→partner) and Y-score (partner→SP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Renal vesicle formation →	+1.064	+0.067	<.001	.002	3	8
OVARY	Metanephric renal vesicle formation →	+1.064	+0.067	<.001	.002	3	8
LUNG_NSCLC_LUAD	Epigenetic regulation of gene expression →	+0.026	+0.048	<.001	.008	3	8
SOFT_TISSUE	Negative regulation of transcription by RNA polymerase III →	+0.092	+0.048	<.001	<.001	3	7
LIVER	Cytoplasmic translation →	+0.041	+0.018	.008	.004	3	7
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.070	+0.059	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 892 associations by consensus.

Renal vesicle formation by SP7 expression — OVARY

Explore this box plot interactively →