SP7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SP7 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SP7-associated genes across cancer lineages are SMIM28. Each is linked with SP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP7-to-partner and partner-to-SP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM28 grouped by SP7-low versus SP7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP7→partner) and Y-score (partner→SP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADSMIM28 →+0.038+5.228<.001.00531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SMIM28 by SP7 expression — LUNG_NSCLC_LUAD

Box plot of SMIM28 in SP7-low vs SP7-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration