Across TCGA patient cohorts, SP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,841 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SP6-associated proteins across cancer lineages are SPR, RCN1, and IKBIP. Each is linked with SP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both SP6-to-partner and partner-to-SP6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SP6→partner) and Y-score (partner→SP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPR →	-0.447	-0.568	.001	.008	3	6
BRCA	RCN1 →	+0.504	+0.833	<.001	<.001	3	5
GBM	IKBIP →	+0.660	+0.692	<.001	<.001	3	5
LSCC	CKAP4 →	+0.521	+0.663	<.001	.002	3	5
OV	COL12A1 →	+1.133	+1.226	<.001	<.001	3	5
OV	EMILIN1 →	+1.031	+1.177	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,841 associations by consensus.

Exploration

SP6 survival (RNA) · tumor vs normal (RNA) · all SP6 data types