Across TCGA patient cohorts, SP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,968 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SP5-associated proteins across cancer lineages are KLC4, PROX1_S511, and MSX2_S91. Each is linked with SP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SP5-to-partner and partner-to-SP5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SP5→partner) and Y-score (partner→SP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KLC4 →	+0.474	+0.640	<.001	<.001	3	4
UCEC	PROX1_S511 →	+1.199	+3.132	<.001	<.001	3	3
COAD	MSX2_S91 →	+1.231	+1.679	<.001	.004	3	3
CCRCC	SUCO_S1081 →	+0.533	+0.611	.004	.002	3	3
UCEC	PROX1_S199 →	+0.995	+2.009	<.001	<.001	3	3
GBM	PTPRC →	-0.504	-0.621	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,968 associations by consensus.

Exploration

SP5 survival (RNA) · tumor vs normal (RNA) · all SP5 data types