Across TCGA patient cohorts, SP5 mutation is significantly associated with the RNA expression of many other genes, with 660 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SP5-associated genes across cancer lineages are SNORD56B, RN7SL810P, and MRPS21P7. Each is linked with SP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP5-to-partner and partner-to-SP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP5→partner) and Y-score (partner→SP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORD56B →	+0.375	+4.822	<.001	.006	3	2
CESC	RN7SL810P →	+0.169	+4.874	.004	.002	3	2
HNSC	MRPS21P7 →	+0.220	+5.339	<.001	.003	3	2
HNSC	MIR3908 →	+0.223	+5.111	<.001	.004	3	2
UCEC	MIR7155 →	+0.429	+3.235	<.001	.001	3	2
UCEC	PDCL2P1 →	+0.153	+3.025	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 660 associations by consensus.

Exploration

SP5 survival (RNA) · tumor vs normal (RNA) · all SP5 data types