SP4

Across TCGA patient cohorts, SP4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,722 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SP4-associated genes across cancer lineages are RAB39B, PSIP1, and GLCCI1. Each is linked with SP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SP4-to-partner and partner-to-SP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SP4 versus RAB39B in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP4→partner) and Y-score (partner→SP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB39B →	+0.744	+0.360	<.001	<.001	3	6
GBM	PSIP1 →	+0.649	+0.506	<.001	<.001	3	6
GBM	GLCCI1 →	+0.949	+0.559	<.001	<.001	3	5
BRCA	CD5 →	+0.990	+0.367	<.001	<.001	3	5
BRCA	KLRB1 →	+0.817	+0.342	<.001	<.001	3	5
PDAC	KLRG1 →	+0.650	+0.334	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,722 associations by consensus.

SP4 vs RAB39B — HNSC

Explore this scatter interactively →