Across TCGA patient cohorts, SP140L RNA expression is significantly associated with the protein abundance of many other proteins, with 13,109 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SP140L-associated proteins across cancer lineages are SP140L_S180, NMI, and PSMB10. Each is linked with SP140L in more than 9 cancer types. Because this analysis shows association rather than direction, both SP140L-to-partner and partner-to-SP140L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SP140L→partner) and Y-score (partner→SP140L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SP140L_S180 →	+1.066	+0.775	.001	.007	3	10
OV	NMI →	+0.588	+1.145	<.001	<.001	3	9
UCEC	PSMB10 →	+0.627	+0.917	<.001	<.001	3	8
GBM	GBP4 →	+0.707	+0.624	<.001	.001	3	8
OV	IFI35 →	+0.570	+1.213	<.001	<.001	3	8
OV	TAP1 →	+0.978	+1.180	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,109 associations by consensus.

Exploration

SP140L survival (RNA) · tumor vs normal (RNA) · all SP140L data types