Across TCGA cell cohorts, SP140L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,723 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SP140L-associated GO terms across cancer lineages are Viral gene expression, Regulation of intracellular transport, and Regulation of intracellular protein transport. Each is linked with SP140L in more than 13 cancer types. Because this analysis shows association rather than direction, both SP140L-to-partner and partner-to-SP140L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SP140L→partner) and Y-score (partner→SP140L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Viral gene expression →	+0.106	+1.138	<.001	<.001	3	14
BONE	Regulation of intracellular transport →	+0.074	+2.869	<.001	<.001	3	14
BONE	Regulation of intracellular protein transport →	+0.078	+2.526	.001	.003	3	13
BREAST	Type II interferon-mediated signaling pathway →	+0.209	+1.671	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to vacuole →	+0.078	+1.153	<.001	<.001	3	13
BLOOD_Lymphoma	Cytoplasmic pattern recognition receptor signaling pathway →	+0.062	+0.806	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,723 associations by consensus.

Exploration

SP140L survival (RNA) · tumor vs normal (RNA) · all SP140L data types