SP110

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SP110 protein abundance is significantly associated with the RNA expression of many other genes, with 13,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SP110-associated genes across cancer lineages are SAMHD1, OAS2, and IFIH1. Each is linked with SP110 in more than 8 cancer types. Because this analysis shows association rather than direction, both SP110-to-partner and partner-to-SP110 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SP110 versus SAMHD1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP110→partner) and Y-score (partner→SP110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSAMHD1 →+0.930+0.455.001.00139
GBMOAS2 →+1.285+0.542<.001<.00139
HNSCIFIH1 →+1.039+0.652<.001<.00139
LSCCZBP1 →+1.228+0.567<.001<.00139
GBMEPSTI1 →+1.079+0.507<.001<.00139
HNSCOASL →+1.356+0.515<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,178 associations by consensus.

SP110 vs SAMHD1 — UCEC

Per-sample scatter of SP110 vs SAMHD1 in UCEC (Pearson r = 0.38).

Explore this scatter interactively →

Exploration