SP100

Across TCGA patient cohorts, SP100 RNA expression is significantly associated with the RNA expression of many other genes, with 20,102 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SP100-associated genes across cancer lineages are DDX58, OAS3, and OAS2. Each is linked with SP100 in more than 33 cancer types. Because this analysis shows association rather than direction, both SP100-to-partner and partner-to-SP100 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SP100 versus DDX58 in SKCM, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP100→partner) and Y-score (partner→SP100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DDX58 →	+1.542	+1.125	<.001	<.001	3	34
DLBC	OAS3 →	+2.246	+0.786	<.001	<.001	3	34
UCS	OAS2 →	+2.088	+1.200	<.001	<.001	3	34
UVM	BTN3A3 →	+1.479	+1.029	<.001	<.001	3	34
SKCM	IFIH1 →	+1.911	+1.246	<.001	<.001	3	34
SCLC	GBP1 →	+2.239	+1.705	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,102 associations by consensus.

SP100 vs DDX58 — SKCM

Explore this scatter interactively →