Across TCGA cell cohorts, SP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,432 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SP1-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Negative regulation of telomere maintenance, and Cilium-dependent cell motility. Each is linked with SP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SP1-to-partner and partner-to-SP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SP1→partner) and Y-score (partner→SP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.118	-0.989	<.001	<.001	3	16
BONE	Negative regulation of telomere maintenance →	+0.092	+0.710	<.001	<.001	3	16
OESOPHAGUS	Cilium-dependent cell motility →	-0.118	-0.989	<.001	<.001	3	16
OESOPHAGUS	Cilium movement involved in cell motility →	-0.120	-1.038	<.001	<.001	3	16
BONE	Regulation of sister chromatid cohesion →	+0.178	+1.019	<.001	<.001	3	15
BONE	Viral translational termination-reinitiation →	+0.112	+0.933	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,432 associations by consensus.

Exploration

SP1 survival (RNA) · tumor vs normal (RNA) · all SP1 data types