SOX7

Across TCGA cell cohorts, SOX7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,355 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SOX7-associated GO terms across cancer lineages are Positive regulation of dopamine receptor signaling pathway, Nucleoside biosynthetic process, and Sister chromatid segregation. Each is linked with SOX7 in more than 6 cancer types. Because this analysis shows association rather than direction, both SOX7-to-partner and partner-to-SOX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of dopamine receptor signaling pathway grouped by SOX7-low versus SOX7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX7→partner) and Y-score (partner→SOX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of dopamine receptor signaling pathway →	+0.232	+0.905	<.001	.003	3	7
PANCREAS	Nucleoside biosynthetic process →	+0.121	+2.722	<.001	<.001	3	7
KIDNEY	Sister chromatid segregation →	+0.078	+0.815	.003	.004	3	7
KIDNEY	Positive regulation of cell cycle checkpoint →	+0.153	+0.985	<.001	.002	3	7
BREAST	Purine nucleoside biosynthetic process →	+0.138	+0.669	<.001	.001	3	7
BREAST	Purine ribonucleoside biosynthetic process →	+0.138	+0.669	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,355 associations by consensus.

Positive regulation of dopamine receptor signaling pathway by SOX7 expression — BREAST

Explore this box plot interactively →