SOX5P1

Across TCGA pan-cancer cohorts, SOX5P1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SOX5P1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SOX5P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SOX5P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and TGCT show a favorable association.

LUAD, KIRP, and STAD are the cancer types where SOX5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.346	0.679	<.001	111	view →
KIRP	DFS	Tertile	All	0.139	0.608	<.001	63	view →
STAD	OS	Tertile	All	0.212	0.428	.001	51	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
ACC	DFS	Tertile	All	0.096	0.646	<.001	24	view →
LGG	OS	Tertile	All	0.249	0.498	.004	18	view →
LIHC	DFS	Tertile	II,III,IV	0.136	0.468	.039	18	view →
OV	DFS	Tertile	IV	0.259	0.483	.035	18	view →
KIRC	DFS	Tertile	III,IV	0.575	0.760	.036	6	view →
SKCM	OS	Tertile	II,III,IV	0.395	0.278	.031	4	view →
SARC	OS	Tertile	All	0.770	0.874	.030	3	view →
TGCT	DFS	Quartile	All	0.848	0.581	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

SOX5P1–LUAD (OS)

Open the LUAD breakdown →