SOX30

Across TCGA patient cohorts, SOX30 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,156 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SOX30-associated GO terms across cancer lineages are Regulation of proteasomal ubiquitin-dependent protein catabolic process, Regulation of telomere maintenance, and mRNA 3'-end processing. Each is linked with SOX30 in more than 27 cancer types. Because this analysis shows association rather than direction, both SOX30-to-partner and partner-to-SOX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal ubiquitin-dependent protein catabolic process grouped by SOX30-low versus SOX30-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX30→partner) and Y-score (partner→SOX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.052	+0.345	<.001	.008	1	28
DLBC	Regulation of telomere maintenance →	+0.061	+0.762	<.001	<.001	3	26
ESCA	mRNA 3'-end processing →	+0.060	+0.806	<.001	<.001	3	25
UCS	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.055	+0.573	<.001	.005	3	25
ESCA	Protein modification by small protein removal →	+0.066	+0.719	.005	<.001	2	26
DLBC	Telomere maintenance via telomere lengthening →	+0.060	+0.747	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,156 associations by consensus.

Regulation of proteasomal ubiquitin-dependent protein catabolic process by SOX30 expression — STAD

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