SOX30

Across TCGA cell cohorts, SOX30 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,512 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOX30-associated GO terms across cancer lineages are Acrosome assembly, Negative regulation of epithelial cell apoptotic process, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SOX30 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOX30-to-partner and partner-to-SOX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acrosome assembly grouped by SOX30-low versus SOX30-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX30→partner) and Y-score (partner→SOX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Acrosome assembly →	-0.056	-0.106	.003	.003	3	8
LUNG_NSCLC_LUAD	Negative regulation of epithelial cell apoptotic process →	+0.068	+0.385	.004	.007	3	7
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.067	+0.161	.004	.006	2	8
SOFT_TISSUE	Regulation of protein modification by small protein conjugation or removal →	+0.044	+0.060	.003	.005	2	7
BREAST	Regulation of apoptotic signaling pathway →	+0.067	+0.355	.001	.002	1	8
KIDNEY	Negative regulation of intrinsic apoptotic signaling pathway →	+0.072	+0.090	.007	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

Acrosome assembly by SOX30 expression — SKIN

Explore this box plot interactively →