SOX3

Across TCGA patient cohorts, SOX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,901 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SOX3-associated GO terms across cancer lineages are Mitochondrial cytochrome c oxidase assembly, U2-type prespliceosome assembly, and NADH dehydrogenase complex assembly. Each is linked with SOX3 in more than 11 cancer types. Because this analysis shows association rather than direction, both SOX3-to-partner and partner-to-SOX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial cytochrome c oxidase assembly grouped by SOX3-low versus SOX3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX3→partner) and Y-score (partner→SOX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.060	+0.066	<.001	<.001	3	12
STAD	U2-type prespliceosome assembly →	+0.057	+0.059	<.001	<.001	3	11
STAD	NADH dehydrogenase complex assembly →	+0.059	+0.076	<.001	<.001	3	10
STAD	Positive regulation of mitotic cell cycle →	+0.053	+0.056	<.001	<.001	3	10
STAD	Ribose phosphate biosynthetic process →	+0.043	+0.063	<.001	<.001	3	10
STAD	Respiratory chain complex IV assembly →	+0.039	+0.057	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,901 associations by consensus.

Mitochondrial cytochrome c oxidase assembly by SOX3 expression — STAD

Explore this box plot interactively →