Across TCGA patient cohorts, SOX18 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,324 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SOX18-associated proteins across cancer lineages are VWF, COL15A1, and FERMT2. Each is linked with SOX18 in more than 6 cancer types. Because this analysis shows association rather than direction, both SOX18-to-partner and partner-to-SOX18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX18→partner) and Y-score (partner→SOX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VWF →	+0.589	+0.984	<.001	<.001	3	7
UCEC	COL15A1 →	+0.684	+0.570	<.001	<.001	3	7
UCEC	FERMT2 →	+0.724	+0.645	<.001	<.001	3	7
UCEC	FMNL3 →	+0.510	+0.775	<.001	<.001	3	7
OV	HSPG2 →	+0.489	+0.815	<.001	.001	3	7
OV	PCOLCE →	+0.849	+1.086	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,324 associations by consensus.

Exploration

SOX18 survival (RNA) · tumor vs normal (RNA) · all SOX18 data types