Across TCGA cell cohorts, SOX18 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,685 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SOX18-associated GO terms across cancer lineages are Myeloid leukocyte mediated immunity, Membrane bending, and Endocardium formation. Each is linked with SOX18 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOX18-to-partner and partner-to-SOX18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX18→partner) and Y-score (partner→SOX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Myeloid leukocyte mediated immunity →	-0.093	-0.853	.006	.001	3	8
PANCREAS	Membrane bending →	-0.161	-0.903	.001	<.001	3	8
BLOOD_Leukemia	Endocardium formation →	+0.599	+1.202	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Ganglioside metabolic process →	+0.108	+0.570	<.001	.001	3	7
PANCREAS	Regulation of sodium ion export across plasma membrane →	-0.186	-0.604	<.001	.001	3	7
PANCREAS	Positive regulation of sodium ion export across plasma membrane →	-0.186	-0.604	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,685 associations by consensus.

Exploration

SOX18 survival (RNA) · tumor vs normal (RNA) · all SOX18 data types