Across TCGA cell cohorts, SOX18 protein abundance is significantly associated with the RNA expression of many other genes, with 3,425 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SOX18-associated genes across cancer lineages are RARS1, H4C15, and ZNF709. Each is linked with SOX18 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOX18-to-partner and partner-to-SOX18 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX18→partner) and Y-score (partner→SOX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RARS1 →	+0.760	+0.631	.002	.006	3	8
URINARY_TRACT	H4C15 →	-2.114	-1.392	.002	<.001	3	6
STOMACH	ZNF709 →	-0.546	-0.618	.003	.001	3	6
LUNG_SCLC	CHCHD4 →	+0.956	+0.549	.001	.005	3	5
OVARY	LETM2 →	+1.877	+0.679	.003	.005	3	5
LUNG_SCLC	CDC42BPG →	-2.235	-0.511	<.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,425 associations by consensus.

Exploration

SOX18 survival (RNA) · tumor vs normal (RNA) · all SOX18 data types