SOX13

Across TCGA patient cohorts, SOX13 protein abundance is significantly associated with the RNA expression of many other genes, with 12,382 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOX13-associated genes across cancer lineages are ZNF711, SRSF5, and BRMS1L. Each is linked with SOX13 in more than 4 cancer types. Because this analysis shows association rather than direction, both SOX13-to-partner and partner-to-SOX13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX13 versus ZNF711 in HNSC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX13→partner) and Y-score (partner→SOX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF711 →	+1.749	+0.929	<.001	<.001	3	5
CCRCC	SRSF5 →	+0.364	+0.463	<.001	<.001	3	4
LSCC	BRMS1L →	+0.615	+0.332	<.001	<.001	3	4
HNSC	CLUAP1 →	+0.782	+0.681	<.001	.001	3	4
LSCC	IL21R →	-0.860	-0.606	<.001	<.001	3	4
GBM	VDR →	-0.997	-0.382	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,382 associations by consensus.

SOX13 vs ZNF711 — HNSC

Explore this scatter interactively →