SOX13

Across TCGA patient cohorts, SOX13 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,653 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOX13-associated proteins across cancer lineages are SOX13_S83, SOX13_S386, and ZNF219_S114. Each is linked with SOX13 in more than 5 cancer types. Because this analysis shows association rather than direction, both SOX13-to-partner and partner-to-SOX13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX13 versus SOX13_S83 in HNSC, with a Pearson correlation of 0.93.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX13→partner) and Y-score (partner→SOX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SOX13_S83 →	+1.150	+1.434	<.001	<.001	3	6
LSCC	SOX13_S386 →	+1.576	+1.148	.004	<.001	2	6
HNSC	ZNF219_S114 →	+0.937	+0.796	.004	.002	2	6
GBM	SAFB2 →	+0.283	+0.478	<.001	<.001	3	5
UCEC	ARID1A →	+0.337	+0.233	<.001	<.001	3	5
LSCC	SOX13_S310 →	+1.057	+0.612	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,653 associations by consensus.

SOX13 vs SOX13_S83 — HNSC

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