SOX13

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SOX13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,421 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SOX13-associated GO terms across cancer lineages are Gamma-delta T cell differentiation, Positive regulation of gamma-delta T cell differentiation, and Positive regulation of gamma-delta T cell activation. Each is linked with SOX13 in more than 14 cancer types. Because this analysis shows association rather than direction, both SOX13-to-partner and partner-to-SOX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-delta T cell differentiation grouped by SOX13-low versus SOX13-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX13→partner) and Y-score (partner→SOX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTGamma-delta T cell differentiation →+1.125+2.291.001<.001315
SOFT_TISSUEPositive regulation of gamma-delta T cell differentiation →+1.002+1.714<.001<.001312
SOFT_TISSUEPositive regulation of gamma-delta T cell activation →+1.127+1.721<.001<.001312
SOFT_TISSUERegulation of gamma-delta T cell differentiation →+0.876+1.769<.001<.00139
BLOOD_LymphomaNegative regulation of myoblast fusion →+0.122+0.998<.001<.00139
PANCREASCerebral cortex radially oriented cell migration →+0.092+0.821<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,421 associations by consensus.

Gamma-delta T cell differentiation by SOX13 expression — URINARY_TRACT

Box plot of Gamma-delta T cell differentiation in SOX13-low vs SOX13-high samples in URINARY_TRACT.

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Exploration