SOX12

Across TCGA cell cohorts, SOX12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,565 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SOX12-associated GO terms across cancer lineages are Metanephric proximal tubule development, Calcium-independent cell-matrix adhesion, and Regulation of nucleotide-excision repair. Each is linked with SOX12 in more than 14 cancer types. Because this analysis shows association rather than direction, both SOX12-to-partner and partner-to-SOX12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric proximal tubule development grouped by SOX12-low versus SOX12-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX12→partner) and Y-score (partner→SOX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Metanephric proximal tubule development →	+0.289	+1.637	<.001	<.001	3	15
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.239	+1.999	<.001	<.001	3	14
STOMACH	Regulation of nucleotide-excision repair →	+0.107	+0.942	<.001	.005	3	13
BONE	Heterochromatin formation →	+0.098	+1.333	<.001	.001	3	13
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.122	+1.034	.008	.006	3	13
BONE	Epigenetic regulation of gene expression →	+0.110	+1.626	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,565 associations by consensus.

Metanephric proximal tubule development by SOX12 expression — PANCREAS

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