SOX10

Across TCGA cell cohorts, SOX10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,260 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SOX10-associated GO terms across cancer lineages are Neutrophil-mediated killing of fungus, Signal transduction in response to DNA damage, and Response to anesthetic. Each is linked with SOX10 in more than 9 cancer types. Because this analysis shows association rather than direction, both SOX10-to-partner and partner-to-SOX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil-mediated killing of fungus grouped by SOX10-low versus SOX10-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX10→partner) and Y-score (partner→SOX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.213	+0.188	.003	.003	3	10
OESOPHAGUS	Signal transduction in response to DNA damage →	+0.078	+0.197	<.001	.004	3	10
KIDNEY	Response to anesthetic →	-0.144	-0.154	<.001	.001	3	9
SKIN	Internal peptidyl-lysine acetylation →	+0.147	+4.802	<.001	<.001	3	9
OESOPHAGUS	RNA catabolic process →	+0.051	+0.128	.001	.001	3	8
OESOPHAGUS	RNA localization →	+0.104	+0.158	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,260 associations by consensus.

Neutrophil-mediated killing of fungus by SOX10 expression — URINARY_TRACT

Explore this box plot interactively →