SOX1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,503 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOX1-associated proteins across cancer lineages are MYEF2, PRKACB, and NIPBL_S2658. Each is linked with SOX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SOX1-to-partner and partner-to-SOX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX1→partner) and Y-score (partner→SOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMYEF2 →+0.485+0.410<.001.00633
GBMPRKACB →+0.382+1.244<.001<.00132
LSCCNIPBL_S2658 →+0.389+0.144.001.00332
GBMTBCC →+0.230+1.061.002<.00132
GBMZNF462_S2172 →+0.491+1.117<.001<.00132
GBMZNF608_T481 →+0.522+0.917<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,503 associations by consensus.

Exploration