Across TCGA cell cohorts, SOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,084 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SOX1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Nucleic acid transport, and RNA transport. Each is linked with SOX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SOX1-to-partner and partner-to-SOX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX1→partner) and Y-score (partner→SOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.071	+3.153	<.001	.001	3	6
BONE	Nucleic acid transport →	+0.113	+3.552	.002	<.001	3	5
BONE	RNA transport →	+0.113	+3.552	.002	<.001	3	5
BONE	Establishment of RNA localization →	+0.109	+3.215	.002	.002	3	5
BONE	RNA localization →	+0.108	+2.488	.003	.003	3	5
OESOPHAGUS	Regulation of translational initiation →	+0.075	+0.565	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,084 associations by consensus.

Exploration

SOX1 survival (RNA) · tumor vs normal (RNA) · all SOX1 data types