Across TCGA patient cohorts, SOWAHD mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHD-associated genes across cancer lineages are FOXO3a_pS318_S321, Ku80, and MIG-6. Each is linked with SOWAHD in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHD-to-partner and partner-to-SOWAHD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHD→partner) and Y-score (partner→SOWAHD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.169	-3.160	.006	.019	3	1
UCEC	Ku80 →	+0.358	+3.009	.002	.019	3	1
UCEC	MIG-6 →	+0.111	+2.179	.026	.034	3	1
UCEC	p62 Lck ligand →	+0.407	+2.321	.012	.035	3	1
UCEC	PKC-b-II_pS660 →	-0.380	-3.169	.006	.019	3	1
UCEC	SLC1A5 →	-0.515	-2.314	.015	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

SOWAHD survival (RNA) · tumor vs normal (RNA) · all SOWAHD data types