Across TCGA patient cohorts, SOWAHB mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHB-associated genes across cancer lineages are STAT3_pY705, ACC1, and eEF2. Each is linked with SOWAHB in more than 2 cancer types. Because this analysis shows association rather than direction, both SOWAHB-to-partner and partner-to-SOWAHB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHB→partner) and Y-score (partner→SOWAHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.429	-2.584	<.001	.010	3	3
SKCM	ACC1 →	+0.397	+3.000	.025	.036	3	2
UCEC	eEF2 →	+0.478	+3.321	<.001	.010	3	2
UCEC	PKC-delta_pS664 →	-0.106	-1.874	.028	.049	3	2
UCEC	TIGAR →	+0.132	+1.512	.031	.035	3	2
SKCM	PKC-a_pS657 →	-0.571	-3.000	.010	.036	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

SOWAHB survival (RNA) · tumor vs normal (RNA) · all SOWAHB data types