Across TCGA cell cohorts, SOWAHB mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SOWAHB-associated genes across cancer lineages are IZUMO3, ZAN, and CALHM4. Each is linked with SOWAHB in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHB-to-partner and partner-to-SOWAHB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHB→partner) and Y-score (partner→SOWAHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IZUMO3 →	+0.029	+4.947	<.001	.001	3	1
BLOOD_Leukemia	ZAN →	+0.092	+4.455	<.001	<.001	3	1
BLOOD_Leukemia	CALHM4 →	+0.024	+3.684	<.001	.004	3	1
BLOOD_Leukemia	SOX14 →	+0.004	+3.684	<.001	.004	3	1
BLOOD_Leukemia	KRTAP4-4 →	+0.013	+4.569	<.001	.003	3	1
BLOOD_Leukemia	PPIAL4D →	+0.135	+3.954	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

SOWAHB survival (RNA) · tumor vs normal (RNA) · all SOWAHB data types