Across TCGA pan-cancer cohorts, SOWAHA mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SOWAHA data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SOWAHA mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SOWAHA expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where SOWAHA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.179	0.840	.004	20	view →
CCRCC	OS	Median	II,III,IV	0.629	0.894	.042	2	view →
GBM	DFS	Quartile	All	0.928	0.528	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SOWAHA tumor-vs-normal RNA expression · all SOWAHA data types