Across TCGA patient cohorts, SOWAHA mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHA-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and ACC_pS79. Each is linked with SOWAHA in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHA-to-partner and partner-to-SOWAHA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHA→partner) and Y-score (partner→SOWAHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.106	-3.432	.008	.005	3	1
UCEC	EGFR_pY1068 →	-0.263	-3.321	.009	.009	3	1
UCEC	ACC_pS79 →	+0.300	+1.906	.031	.016	3	1
UCEC	GATA6 →	-0.146	-1.693	.026	.044	3	1
UCEC	ACC1 →	+0.385	+3.013	.008	.018	3	1
UCEC	Heregulin →	-0.126	-2.308	.011	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

SOWAHA survival (RNA) · tumor vs normal (RNA) · all SOWAHA data types