Across TCGA cell cohorts, SOWAHA mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SOWAHA-associated genes across cancer lineages are LCE2C, KRTAP10-1, and SULT6B1. Each is linked with SOWAHA in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHA-to-partner and partner-to-SOWAHA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHA→partner) and Y-score (partner→SOWAHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LCE2C →	+0.023	+4.078	<.001	.009	3	2
SOFT_TISSUE	KRTAP10-1 →	+0.058	+5.369	<.001	.004	3	1
SKIN	SULT6B1 →	+0.105	+2.657	<.001	.007	3	1
SKIN	LRP1B →	+0.366	+3.362	<.001	.005	3	1
SKIN	C2CD4B →	+0.033	+3.099	<.001	.002	3	1
BLOOD_Leukemia	EPPIN →	+0.005	+4.507	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

SOWAHA survival (RNA) · tumor vs normal (RNA) · all SOWAHA data types