SOSTDC1

Across TCGA patient cohorts, SOSTDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,547 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOSTDC1-associated proteins across cancer lineages are PSME2, SKAP2, and PARP14. Each is linked with SOSTDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SOSTDC1-to-partner and partner-to-SOSTDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOSTDC1 versus PSME2 in LSCC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOSTDC1→partner) and Y-score (partner→SOSTDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSME2 →	-0.292	-1.659	<.001	<.001	3	5
OV	SKAP2 →	-0.473	-1.417	<.001	.001	3	5
HNSC	PARP14 →	-0.393	-1.688	<.001	.001	3	5
OV	ITGB2 →	-0.517	-1.987	.008	<.001	2	5
BRCA	NDRG2 →	+0.611	+1.828	<.001	<.001	3	4
HNSC	UBE2L6 →	-0.551	-1.243	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,547 associations by consensus.

SOSTDC1 vs PSME2 — LSCC

Explore this scatter interactively →