SOSTDC1

Across TCGA cell cohorts, SOSTDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOSTDC1-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Regulation of cytoplasmic translation, and Aerobic respiration. Each is linked with SOSTDC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOSTDC1-to-partner and partner-to-SOSTDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by SOSTDC1-low versus SOSTDC1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOSTDC1→partner) and Y-score (partner→SOSTDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.086	+1.561	<.001	.002	3	8
OVARY	Regulation of cytoplasmic translation →	+0.122	+2.196	<.001	<.001	3	8
BREAST	Aerobic respiration →	+0.045	+1.658	.007	.004	3	7
BONE	Regulation of RNA splicing →	+0.068	+0.802	.002	.008	3	7
BONE	Proteasomal ubiquitin-independent protein catabolic process →	+0.069	+1.328	.001	<.001	3	7
PANCREAS	Electron transport chain →	+0.076	+1.228	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,362 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by SOSTDC1 expression — OVARY

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