SORD

Across TCGA patient cohorts, SORD protein abundance is significantly associated with the RNA expression of many other genes, with 12,168 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SORD-associated genes across cancer lineages are SORD2P, PDE1B, and BATF3. Each is linked with SORD in more than 8 cancer types. Because this analysis shows association rather than direction, both SORD-to-partner and partner-to-SORD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SORD versus SORD2P in OV, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SORD→partner) and Y-score (partner→SORD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SORD2P →	+1.155	+0.938	<.001	<.001	3	9
OV	PDE1B →	-0.990	-0.771	<.001	<.001	3	6
LUAD	BATF3 →	-0.715	-0.282	<.001	.006	3	6
COAD	GBGT1 →	-0.614	-0.350	<.001	.001	3	6
BRCA	CSF2RA →	-0.789	-0.742	<.001	<.001	3	6
UCEC	SPINT1-AS1 →	+0.930	+0.532	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,168 associations by consensus.

SORD vs SORD2P — OV

Explore this scatter interactively →