SORD

Across TCGA patient cohorts, SORD mutation is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SORD-associated genes across cancer lineages are RNU1-48P, CTHRC1P1, and RNU7-175P. Each is linked with SORD in more than 1 cancer types. Because this analysis shows association rather than direction, both SORD-to-partner and partner-to-SORD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-48P grouped by SORD-low versus SORD-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SORD→partner) and Y-score (partner→SORD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-48P →	+0.179	+7.640	<.001	.009	3	2
UCEC	CTHRC1P1 →	+0.112	+2.957	.001	.009	3	1
CESC	RNU7-175P →	+0.667	+5.010	<.001	.009	3	1
CESC	MTND5P35 →	+0.028	+5.539	<.001	.004	3	1
CESC	HNRNPMP2 →	+0.100	+6.342	<.001	.001	3	1
CESC	TBC1D3H →	+0.025	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

RNU1-48P by SORD expression — BLCA

Explore this box plot interactively →