SORD

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SORD protein abundance is significantly associated with the RNA expression of many other genes, with 7,212 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SORD-associated genes across cancer lineages are FA2H, TCOF1, and SLC1A3. Each is linked with SORD in more than 6 cancer types. Because this analysis shows association rather than direction, both SORD-to-partner and partner-to-SORD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SORD versus FA2H in LUNG_NSCLC_LUAD, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SORD→partner) and Y-score (partner→SORD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADFA2H →-1.537-0.790<.001<.00137
LUNG_NSCLC_LUADTCOF1 →+0.529+0.661.003.00137
PANCREASSLC1A3 →+2.715+0.735<.001<.00137
PANCREASCLCN3 →-0.824-0.695.004.00136
LUNG_NSCLC_LUADTHOC3 →+0.537+0.602.005.00536
OESOPHAGUSSPART →+3.065+0.817<.001.00236
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,212 associations by consensus.

SORD vs FA2H — LUNG_NSCLC_LUAD

Per-sample scatter of SORD vs FA2H in LUNG_NSCLC_LUAD (Pearson r = -0.45).

Explore this scatter interactively →

Exploration